The next frontier in the genome sciences will be developing technology that captures novel quantitative biological measurements ... more about genomics
Genome Wowser
The Center for Biomedical Informatics (directed by PGFI member Peter White) at The Children's Hospital of Philadelphia has developed Genome Wowser (cost: free). Genome Wowser provides an iPad-enabled view of the human genome that is intuitive, highly portable and allows a “Google Maps”-like navigation experience of the popular UCSC Genome Browser.
Eukaryotic Pathogen Database Resources
EuPathDB Bioinformatics Resource Center for Biodefense and Emerging/Re-emerging Infectious Diseases is a portal for accessing genomic-scale datasets associated with the eukaryotic pathogens (Cryptosporidium, Giardia, Leishmania, Neospora, Plasmodium, Toxoplasma, Trichomonas and Trypanosoma).
http://eupathdb.org
PTM-Switchboard
Transcriptional regulation by sequence-specific transcription factors (TFs) is mediated, in significant part, by the post-translational modifications (PTMs) of the TFs. PTMs serve as ‘molecular switchboards’ that map upstream signaling events to the downstream transcriptional events. PTM-Switchboard is designed to catalog known cases of TF-PTMs affecting gene transcriptions. The current version 1.0 is limited to the model organism S. cerevisiae (budding yeast).
http://cagr.pcbi.upenn.edu/PTMswitchboard/
Related paper: Everett, L., A. Vo, and S. Hannenhalli, PTM-Switchboard--a database of posttranslational modifications of transcription factors, the mediating enzymes and target genes. Nucleic Acids Res, 2009. 37: p. D66-71.