Single Cell Analysis Symposium

March 12, 2014 @ the University of Pennsylvania

Hold the date for this all-day symposium. Speakers include Nancy Allbritton, Helen Blau, Chi Dang, Jim Eberwine, Junhyong Kim, Christopher Murray, Garry Nolan, Arjun Raj and Sherman Weissman.

More details and registration here for this free event.


The next frontier in the genome sciences will be developing technology that captures novel quantitative biological measurements ... more about genomics


PGFI Members' Research

PGFI members pursue genomics research in one of Penn's 12 Schools, or in nearby institutions, including Children's Hospital of Philadelphia, The Wistar Institute, Thomas Jefferson College of Graduate Students and Monell Chemical Senses Center. Visit our members' pages to learn about the diversity of research performed by PGFI-affiliated investigators.

A selection of PGFI-enabled papers can be found here.

PGFI-Funded Research

PGFI's Pilot Grant Program encourages innovation and technology development in the genome sciences by funding creative, often risky, projects.  Through strategic investments in novel research, PGFI strives to empower the local research community to advance genomics globally.

Requests for applications are typically announced in the fall and spring (RFAs). Penn faculty members from any school are encouraged to apply.

Funded Projects

Descriptions of PGFI-funded proposals can be viewed by clicking on the project title.


Dr. Marija Drndic
Real-time sizing/mass measurement and multi-channel detection of protein molecules extracted from electroporated live cells

Dr. Roger Greenberg
Dynamic imaging of ubiquitination at DNA double-strand breaks

Drs. Brian D. Gregory and Li-San Wang
Genome-wide analysis of the double-stranded RNA component of eukaryotic transcriptomes

Drs. Anna Kashina and Sergei Vinogradov
In vivo imaging of vesicle trafficking and its regulation by protein arginylation

Drs. Barry Cooperman, Yale Goldman and Todd Lamitina
Real-time proteomics (RTP) by single molecule fluorescence microscopy

Dr. Michael Lampson
Measuring phosphorylation dynamics in living cells: from local signaling networks to tumorigenesis

Drs. David Roos and Sara Cherry
Genome-wide siRNA screening in human macrophages to dissect mechanisms of cell-intrinsic immunity against the protozoan parasite Toxoplasma gondii

Dr. Susan Ross
Identification of intracellular molecules required for MMTV entry


Drs. David Artis, Frederic Bushman and Gary Wu
Immune Regulation of Mammalian Microbial Communities

Dr. Haig Kazazian
A Genomic Approach for Identifying New L1 Retrotransposition Events

PGFI Announcements

The PGFI Fall 2013 Newsletter can be viewed here.

Educational Facility Professional Development Workshops can be applied for here.



Based at the University of Pennsylvania, Penn Genome Frontiers Institute (PGFI) is a university-wide institute dedicated to the advancement of the interdisciplinary field of genomics research. PGFI fosters collaborations and scientific exchange across biology, veterinary medicine, pharmacology, medicine, genetics, microbiology, engineering, physics, chemistry and psychology. Our mission...