Milestones

Developed by Penn Investigators, Fostered by PGFI

• Natural Language Processing System for mining the literature for cancer related processes
• A comparative genomics database for neuronal molecular processes
• First application of Hybrid Systems Modeling to systems biology problems
• Penn Center for Molecular Discovery for high-throughput small molecule screening
• Dominant microarray probe generation technology
• In vivo technologies for RNA-RNA Binding Protein characterization
• Chemical agents that increase the efficiency of gene transfections
• The first subcellular compartment transfection technologies
• The prototype of the Bioanalyzer instrumentation
• Longest-running training program in Computational Biology and Bioinformatics
• A robust microRNA detection array platform
• The Genomics Unified Schema (GUS) for storage and analysis of genomics data
• Toxoplama gondii and plasmodium national databases (ToxoDB and PlasmoDB)
• Membership in the consortium that sequenced the first human chromosome (Chromosome 22)
• Leadership in database integration technology including semi-automated schema matching and peer-to-peer integration
• Key role in the NSF Assembling the Tree of Life initiative for computational infrastructure, simulations, and databases